A common method of administering medication is via a trans-dermal patch. These “skin patch” drugs include pain relievers, nicotine, hormones, and drugs to treat angina and motion sickness. The drug is absorbed from the patch, through the outer layers of skin, and into deeper layers. There, it is absorbed into the blood stream and circulated through the body.
What about the chemicals in many skincare products though? Do you want them absorbed into your bloodstream? I can't verify the accuracy of these figures, but it's food for thought.
If I can't eat my skincare without going to the Emergency Department, I don't put it on my skin (or my families).